- February 2, 2018
Is the cell negatively affected, seen from a physiological point of view, by long measurement times?
This does not differ from conventional patch clamp and depends to a large extent on which ion channel…
Read more- February 2, 2018
How is the cell affected by the constant flow and the lateral movement?
Data suggests that the seal becomes stabilized by the flow which means increased stability in the measurements. However,…
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How long is a patch clamped cell stable in the flow?
In our experiments, we have seen an effect of more stable seals and higher resistances when the cell…
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Several substances on the same cell, is this OK?
It is OK as long as the user feels comfortable with it. An internal control substance should always…
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What is the procedure to use the system with adherent cells?
With the present system, the cells need to be dislodged from the surface if they are adherent. We…
Read more- February 2, 2018
Can any type of cell be employed?
The cell should fit with in the diffusion zones of the collimated flow, and the size and shape…
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