Question 1

Dr. Joseph Bruton from Karolinska Institutet

Celine Billerit · Accepted Answer

“I chose the BioPen System because I can target precise areas of the cell and see how local and global calcium changes in response to different perturbations. The small size of the area means that multiple sites can be examined in a single muscle cell.

The BioPen System has several advantages:

small footprint on the lab bench,
small target area, although this can be enlarged quite a bit,
consumption of expensive antibodies and drugs is minimized compared to perfusion of the whole cell as we used to have to do.”

Question 2

Dr. Joseph Bruton from Karolinska Institutet

Celine Billerit · Accepted Answer

“I chose the BioPen System because I can target precise areas of the cell and see how local and global calcium changes in response to different perturbations. The small size of the area means that multiple sites can be examined in a single muscle cell.

The BioPen System has several advantages:

small footprint on the lab bench,
small target area, although this can be enlarged quite a bit,
consumption of expensive antibodies and drugs is minimized compared to perfusion of the whole cell as we used to have to do.”