Biopixlar highlighted in Advanced Materials article

Being able to fabricate functional organs in a laboratory as an alternative to transplanted organs is one of the long-standing visions that for long has been a driving force behind development in biopringting. In the review article Bioprinting of Complex Multicellular Organs with Advanced Functionality—Recent Progress and Challenges Ahead, published November 5 in the journal Advanced Materials, Dr. Luiz E. Bertassoni from Oregon Health and Science University explores the steps that the field has taken towards creating tissue constructs with advanced functionality and brings up some of the critical challenges that yet remains to be solved.

One of the most important challenges to enable fabrication of functional engineered organs is finding a way to replicate the multicellular tissue architecture and to engineer a physiologically relevant extracellular microenvironment. In his review article, Dr. Bertassoni highlights Biopixlar as an interesting technology with the potential to address many of the important challenges that lies ahead for the bioprinting field and states:

“This is a great example of how microfluidics engineering has been utilized to favor the biology of bioprinting. One key advantage of a system like this, is that it enables rapid switching between various cell types, in the middle of the printing run, with relative ease, and as many times as needed. Consequently, the idea of building tissue complexity and cell heterogeneity in a construct becomes a lot more attainable.”

We thank Dr. Bertassoni for his insightful comments on the possibilities and challenges associated with fully realizing the potential of bioprinting. Enabling high precision functional tissue engineering is one of our main goals at Fluicell and we look forward to taking part in taking bioprinting to the next level.

Read the full review article Bioprinting of Complex Multicellular Organs with Advanced Functionality—Recent Progress and Challenges Ahead on the Advanced Materials web page.