Biopixlar ready to face key challenges for bioprinting

As the world of bioprinting moves from concepts to actual biological applications, the performance requirements put on emerging technologies become higher and higher. Biopixlar is well positioned to be a leading technique in this development, with unique performance features in several of the most critical areas, such as bioprinting resolution and cell viability. With Biopixlar, Fluicell is ready to take biopinting to the next level.

In the recent paper The Bioprinting Roadmap, researchers across a wide range of disciplines have made an overview of the state of bioprinting today and identified a set of key challenges for the field to move forward.

The paper presents an interesting perspective on the advancement of the bioprinting field, moving more and more towards using cells as building blocks in printed biological tissue and disease models. For this development to be possible, bioprinting processes need to be able to produce structures with higher resolution and multi-cellular complexity, according to the authors. This also includes the ability to control cell behavior to actively direct cells towards correct functional tissue maturation.

Biopixlar addresses this unmet need by offering unparalleled single-cell resolution with the capacity to print several different cell types at once. Biological tissues and organs have an inherent complexity down to the level of individual cells and it necessary for bioprinted model systems to achieve similar complexity in order to have sufficient functional representation.

Another important challenge identified in The Bioprinting Roadmap is the survivability of the printed cells. With higher resolution bioprinting, the mechanical stress put on the printed cells increases, which leads to lower cell viability. This is in particular true for conventional extrusion bioprinting using bioink. Biopixlar solves this challenge by printing cells directly in culture media and avoiding bioink altogether. This is especially important when printing cells sensitive to shear stress, such as primary cells and stem cells.

Taken together, Biopixlar is well suited to meet upcoming bioprinting challenges and we are excited to see what future development will bring.